Usage guide

How to Use a PDRN Serum: A Simple Morning and Night Guide

Two or three drops, twice a day, in the right place. That is genuinely all there is to it. Here is how to make it feel good and work with what you already own.

Morning routine: pressing serum into the cheek, bottle on the sink

Where a PDRN serum goes in your routine

Serums go on clean skin, before anything thicker. The rule of thumb is thin to thick: cleanse, serum, moisturiser, then sunscreen in the morning. A PDRN serum is a light, watery texture, so it sits first.

Morning, step by step

  1. Cleanse or rinse. If your skin is dry or sensitive, a splash of lukewarm water is enough in the morning.
  2. Apply 2–3 drops to slightly damp skin. Press it in with your palms rather than rubbing; it spreads easily across the face and neck.
  3. Wait about thirty seconds. It absorbs quickly and leaves no film.
  4. Moisturiser, then SPF. Makeup goes on as usual. A light serum underneath tends to make foundation sit better, not worse.

Evening, step by step

  1. Cleanse properly to remove sunscreen and makeup. A single gentle cleanser is enough for most people.
  2. Apply 2–3 drops to the face and neck, pressing gently.
  3. Night cream if you use one. If you don't, that's fine too; many women find the serum alone is comfortable in warmer months.

How much is enough?

Two to three drops covers the face and neck. More does not absorb better; it just takes longer to sink in. One 30 ml bottle lasts roughly a month at this dose, which is why the 3-bottle pack is described as a 3-month routine.

Patch test first

Before the first full application, put a drop on the inner arm and wait 24 hours. If you see redness or feel itching, stop. This is sensible with any new product, and especially if your skin has become more reactive recently.

Layering with other products

  • Vitamin C, retinol, exfoliating acids: a hydrating serum layers under most of them. Introduce one new product at a time so you know what your skin is reacting to.
  • Face oils: always after the serum, never before. Oil on top seals the water in; oil underneath blocks the serum.
  • Sunscreen: always last in the morning, and always.

What it won't do

A serum is a cosmetic product. It can help skin feel hydrated, comfortable and look healthier. It does not treat skin conditions and it is not a substitute for medical care. If something on your skin worries you, see your GP.

The best routine is the one you actually keep up. Two or three drops, twice a day, is easy to keep up.

General skincare information, not medical advice. If you have a skin condition, talk to your GP or dermatologist.